A  collaborative research body aimed at improving sustainability practices of water use in the fringes of Australia's largest cities has been expanded.

The collaborative body, known as Water Management Innovation and Strategy Enhancement Partnership in Peri-urban Research (WISER) Network, will involve local councils, government agencies and the Universities of Western Sydney, Melbourne, New England and RMIT.

The network, which has operated for four years in Western Sydney, includes Blacktown, Hawkesbury, Liverpool and Penrith local councils, the NSW Department of Primary Industries and a number of universities collaborating with local water users to achieve greater harmony in water policy.

The Federal Government is holding a series of information sessions to explain the processes and accessibility of new R&D Tax Incentive.

The Australia Solar Institute is interested in receiving feedback from the Australian solar research community in relation to a proposed Strategic Research Initiative (SRI) funded initially under the auspices of the United States – Australia Solar Energy Collaboration (USASEC).

Australia's first desalination research facility has opened in Rockingham, Western Australia, as a joint venture between State and Federal Governments, and participating research organisations.


Professor Jiri Neuzil from the School of Medical Science and GHI is leading a research team that has developed anti-cancer agents derived from vitamin E (VE), with the capacity to induce programmed cell death, a process known as apoptosis.

"This (chemical modification) potentially represents a new paradigm in efficient anti-cancer therapy. It has a very solid scientific basis because it sends the compounds where they matter most," Professor Neuzil said.

"Thus, the process is much more efficient when the relevant drugs are targeted to mitochondria."

He explained that mitochondria are organelles inside cells that contain their own DNA. While they are essential to supply the cells with energy, mitochondria also contain proteins needed to kill cells.

Working initially with Professor Smith from Otago University in New Zealand and recently with Associate Professor Mark Coster from Griffith's Eskitis Institute, Professor Neuzil has successfully modified the VE-based drugs so that some 90 per cent of the agents localise to mitochondria, triggering the death of cancer cells much more efficiently than the non-targeted counterparts of the agents.

The process has been successfully tested on mice, focusing on breast and colorectal tumours.

"The new compounds don't harm good cells. And they're more efficient than (parental) compounds that don't target mitochondria directly.

"Its potential is huge. We now want to test these agents in other types of tumours, preferably those that are hard to treat."

Using this innovative approach, Professor Neuzil is attempting to 'outwit' cancer cells he describes as 'bloody clever'.

"When cancer cells are exposed to certain agents, their genes mutate as they learn how to resist the drugs."

However, by combining the vitamin E-derived agents with other therapeutic drugs, the cancer cell's attention can be effectively 'distracted', reducing its capacity to mutate.

This combinatorial and, potentially, intermittent form of treatment also serves to reduce negative side-effects through the positive synergy of two or more drugs that exert their cancer cell-killing activity by different mechanisms.

Professor Neuzil's pre-clinical research is also investigating if other recognised anti-cancer drugs are similarly effective in mitochondria when modified in a corresponding way.

To take the research to the important clinical stage, he is hoping to get the attentions and support of a benefactor.

Australian scientists are set to gain access to one of the world’s most powerful synchrotrons following the signing of a Memorandum of Understanding (MOU) with the Japanese SPring-8 Centre.

The South Australian Government is developing a cross-government strategy to increase the supply of people taking up careers in the science, technology, engineering and mathematics fields to meet the future needs of local industry.

A generous gift of $5 million from one of Australia's leading businessmen will enable the University of Sydney to make major advances in the field of nanoscience.

The possibility of redesigning the illicit recreational drug ‘ecstasy' to treat blood cancers is being explored by a team of researchers from The University of Western Australia and the University of Birmingham in England.

A number of senior water researchers have warned of the possible effects of the coal seam gas (CSG) industry on water and salinity.

Western Australia has announced that a National Centre of Excellence for grains research will be build in Perth following an agreement between the State Government and the Grains Research Development Council (GRDC).

The Federal Government has introduced a new research and development tax credit system which will aim to assist small businesses offset the cost of conducting research in their respective fields.

Leading expert Dr Stephen Hanly has been lured back to Australia as the inaugural CSIRO-Macquarie University Chair in Wireless Communications.

An international research project to eliminate dengue fever has  reported successful results from a field trial in which 150,000 mosquitoes infected with a bacterium called Wolbachia that  prevents the dengue virus from growing in the insect were released into two suburbs in Cairns.

An international team of researchers, including Australians, has pioneered a new method of producing superdense aluminum by simulating the conditions found at the centre of the Earth. The superdense aluminum is around 40 per cent stronger and denser than the conventional counterpart.

The Department of Innovation, Industry, Science and Research has called for responses to a consultation paper it released on its 2011 Review of HERDC Category 3 Income.

Nine outstanding Australian researchers have been awarded John Stocker Postdoctoral Fellowships and Postgraduate Scholarships that will allow them to continue to conduct advanced research in their respective areas.

Researchers at RMIT University have explored how thermopower waves in thermoelectric materials can convert heat in solid fuels into electrical energy.

The National Health and Medical Research Council (NHMRC) has introduced its new Standard for Clinical Practice Guidelines to streamline health professional’s access to diagnostic information and treatment.

A new Visualisation Laboratory (VisLab) has been launched at La Trobe University in Victoria, providing sophisticated visualisation technology that will allow researchers to run experiments remotely.

 

VisLab will link to the Australian Synchrotron and other local and international facilities, including those with existing La Trobe remote stations. It will link to analytical equipment at Berlin's BESSY Synchrotron, the Canadian Light Source at Saskatoon and Chicago's Argonne Advanced Photon Source machine. Within VisLab from their remote location, researchers are able to drive the instrument and perform experiments themselves. Alternately they can collaborate in real time with another team of researchers present at the instrument

 

VisLab also doubles as a classroom, promoting and teaching science and technology to high-school and university students.

 

VisLab was funded through the Victorian Government’s Victorian eResearch Strategic Initiative (VeRSI). New funding of $2 million for the initiative has allowed VeRSI's membership to expand to include all of Victoria's eight universities, as well as the Australian Synchrotron and the Victorian Government Department for Primary Industries.

 

VisLab is a collaboration between the La Trobe eResearch Office, the Centre for Materials and Surface Science at La Trobe University and VeRSI.

A new Forensic DNA Laboratory dedicated to forensic DNA research has been opened at Flinders University in South Australia.

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