Lupus patients show more severe symptoms of the disease if their vitamin D levels are low, an Australian-first study has found.

Systemic lupus erythematosus (SLE), which affects more than five million people worldwide, was found to be worse in vitamin D deficient SLE patients than in those with normal levels, in the study led by Professor Eric Morand, head of the Monash Lupus Clinic and Southern Clinical School at Monash Medical Centre.

The research also observed that Australians are more susceptible to the disease due to environmental, genetic and cultural factors, which contribute to vitamin D deficiency.

Professor Morand said although practicing sun avoidance is important for lupus patients, as sunlight can make aspects of the disease worse, this can lead to vitamin D deficiency and an increase in the severity of the disease.

“In multicultural Australia, instances of vitamin D deficiency can be seen in cultural groups where clothing covers the body, in people with dark skin tone who have lower absorption, and those who practice sun avoidance” Professor Morand said.

The findings will be presented at the Annual Scientific Meeting of the Australian Rheumatology Association in Canberra.


The research involved five years of clinical data and blood sample collection from the Monash Lupus Clinic at Monash Medical Centre, the only lupus-dedicated clinic in Australia.